Nervous System



Author: Sjoerd Elias Background: The majority of primary care patients referred for bowel endoscopy do not have significant colorectal disease (SCD), and are – in hindsight – unnecessarily exposed to a small but realistic risk of severe endoscopy-associated complications. We developed a diagnostic strategy to better exclude SCD in these […]

Is there an added value of faecal calprotectin and haemoglobin ...




Author: Hendrik Helmerhorst Background: Although oxygen is generally administered in a liberal manner in the perioperative setting, the effects of oxygen administration on dynamic cardiovascular parameters, filling status and cerebral perfusion have not been fully unraveled. Our aim was to study the acute hemodynamic and microcirculatory changes before, during and […]

Hemodynamic effects of short-term hyperoxia after coronary artery bypass grafting



Author: Elena Dragioti Background: Insomnia is a major cause of concern in the elderly with and without pain. This study set out to examine the insomnia and its correlates in a large sample of community adults aged ≥65 years. Methods: A cross-sectional postal survey was completed by 6205 older individuals (53.8% […]

Insomnia severity and its relationship with demographics, pain features, anxiety, ...


Author: Stéphane Gaudry Background: The recent demonstration of prone position’s strong benefit on patient survival has rendered proning a major therapeutic intervention in severe ARDS. Uncertainties remain as to whether or not ARDS patients in the postoperative period of abdominal surgery should be turned prone because of the risk of […]

Prone positioning in acute respiratory distress syndrome after abdominal surgery: ...



Author: Huisu Eom Background: Our study evaluated the effectiveness of the Workers’ General Health Examination by health examination period and compliance. Methods: A retrospective cohort of the health examination participants in 2006 (baseline year: N = 6,527,045) was used. We identified newly occurring cardio-cerebrovascular disease over 7 years (from 2007 to 2013). After […]

Effectiveness of workers’ general health examination in Korea by health ...


Author: Michael Lanspa Background: In sepsis, tachycardia may indicate low preload, adrenergic stimulation, or both. Adrenergic overstimulation is associated with septic cardiomyopathy. We sought to determine whether tachycardia was associated with left ventricular longitudinal strain, a measure of cardiac dysfunction. We hypothesized an association would primarily exist in patients with […]

Associations among left ventricular systolic function, tachycardia, and cardiac preload ...



Author: Xiaoming Yao Neuromyelitis optica spectrum disorders (herein called NMO) is an inflammatory demyelinating disease of the central nervous system in which pathogenesis involves complement-dependent cytotoxicity (CDC) produced by immunoglobulin G autoantibodies targeting aquaporin-4 (AQP4-IgG) on astrocytes. We reported evidence previously, using CD59 −/− mice, that the membrane-associated complement inhibitor […]

Marked central nervous system pathology in CD59 knockout rats following ...







Author: Gunda Musekamp Background: Heart failure (HF) patient education aims to foster patients’ self-management skills. These are assumed to bring about, in turn, improvements in distal outcomes such as quality of life. The purpose of this study was to test the hypothesis that change in self-reported self-management skills observed after […]

Does improvement in self-management skills predict improvement in quality of ...


Author: Renato De Vecchis The progress of the pharmacological and device treatment of heart failure (HF) has led to a substantial improvement of mortality and rehospitalization. Further potential for improvement may be heralded in the post-discharge management of HF patients, including patient education for self-management of HF. The study by […]

Comorbidity “depression” in heart failure — Potential target of patient ...



Author: Pedro Pallangyo Background: Cardiorenal anemia syndrome (CRAS) is an evolving global epidemic associated with increased morbimortality and cost of care. The management of patients with CRAS remains a challenging undertaking worldwide and the lack of evidence-based clinical guidelines adds to the challenge. We aimed to explore the prevalence and […]

Cardiorenal Anemia Syndrome and Survival among Heart Failure Patients in ...


Author: Kingsley Afeti Background: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common disorders in early childhood. However, not many studies have been conducted on the prevalence and effect of ADHD on school performance in Ghana. This study sought to ascertain the prevalence of ADHD and its effect on school […]

Prevalence and effect of attention-deficit/hyperactivity disorder on school performance among ...




Author: Anne Matthews Background: Increasing levels of physical activity decreases the risk of premature mortality associated with chronic diseases e.g., coronary heart disease, type 2 diabetes, stroke. Despite this, most adults in England do not meet physical activity guidelines. Physical activity advice and signposting offered to at-risk patients by primary […]

An education programme influencing health professionals to recommend exercise to ...



Author: Keith Doram Background: Organizations that encourage the respectful expression of diverse spiritual views have higher productivity and performance, and support employees with greater organizational commitment and job satisfaction. Within healthcare, there is a paucity of studies which define or intervene on the spiritual needs of healthcare workers, or examine […]

Got spirit? The spiritual climate scale, psychometric properties, benchmarking data ...




Author: Lixuan Zhang Background: Despite considerable efforts to encourage participation, even in some developed countries, proportion of patients participating in institution-based cardiac rehabilitation (CR) programs remained sub-optimal. The present study was designed to investigate the acceptability of community health service center (CHSC)-based Cardiac Rehabilitation (CR), and examine its effectiveness in […]

Community health service center-based cardiac rehabilitation in patients with coronary ...


Author: Christoph Correll Background: Serious mental illnesses are associated with increased risk of cardiometabolic comorbidities. The objective of this study was to evaluate the prevalence of cardiometabolic comorbidity and its association with hospitalization outcomes and costs among inpatients with schizophrenia or bipolar disorder. Methods: This retrospective database analysis reviewed patients […]

Cardiometabolic comorbidities, readmission, and costs in schizophrenia and bipolar disorder: ...



Author: Stacey Lok Background: The prevalence of sensitization varies geographically based on multiple environmental factors including humidity. The aim of this study was to determine the prevalence of atopy in symptomatic adults. More importantly we aimed to obtain a regional statistic of sensitization to common allergens given Saskatchewan’s dry climate. […]

Prevalence of allergen sensitization in 1000 adults in Saskatchewan