Stroke


Author: Hendrik Helmerhorst Background: Although oxygen is generally administered in a liberal manner in the perioperative setting, the effects of oxygen administration on dynamic cardiovascular parameters, filling status and cerebral perfusion have not been fully unraveled. Our aim was to study the acute hemodynamic and microcirculatory changes before, during and […]

Hemodynamic effects of short-term hyperoxia after coronary artery bypass grafting




Author: Anne Matthews Background: Increasing levels of physical activity decreases the risk of premature mortality associated with chronic diseases e.g., coronary heart disease, type 2 diabetes, stroke. Despite this, most adults in England do not meet physical activity guidelines. Physical activity advice and signposting offered to at-risk patients by primary […]

An education programme influencing health professionals to recommend exercise to ...




Author: Hsin-Bang Leu Background: Either classic or novel biomarkers have not been well investigated for clinical outcomes of coronary artery disease (CAD) in Asian people especially ethnic Chinese. We reported here a prospective national-based follow-up study that aims to elucidate the clinical profiles and to identify the new biosignatures (especially […]

Identification of new biosignatures for clinical outcomes in stable coronary ...


Author: Milija Mijajlović Post-stroke dementia (PSD) or post-stroke cognitive impairment (PSCI) may affect up to one third of stroke survivors. Various definitions of PSCI and PSD have been described. We propose PSD as a label for any dementia following stroke in temporal relation. Various tools are available to screen and […]

Post-stroke dementia – a comprehensive review



Author: Yan Dai Background: The incidence, clinical outcomes and antithrombotic treatment spectrum of atrial fibrillation (AF) in patients hospitalized with acute myocardial infarction (AMI) have not been well studied in Chinese population. Methods: Twenty-six thousand five hundred ninety-two consecutive patients diagnosed with AMI were enrolled in CAMI registry from January […]

Atrial fibrillation in patients hospitalized with acute myocardial infarction: analysis ...


Author: Faheem Guirgis Background: Dyslipidemia is a risk factor for cardiovascular disease, with elevated low-density lipoprotein cholesterol (LDL-C) and decreased high-density lipoprotein cholesterol (HDL-C) recognized as risk factors for acute coronary events. Studies suggest an association between low cholesterol levels and poor outcomes in acute sepsis. We sought to determine […]

Cholesterol levels and long-term rates of community-acquired sepsis



Author: Chaojie Wei Background: Administration of a selective β1-blocker, such as esmolol, in human septic shock has demonstrated cardiovascular protective effects related to heart rate reduction. Certain experimental data also indicate that esmolol exerts systemic anti-inflammatory and beneficial effects on vascular tone. Thus, the present study aimed to determine whether […]

Effects of low doses of esmolol on cardiac and vascular ...


Author: Xuexian Fang Background: Although studies have examined the association between dietary magnesium intake and health outcome, the results are inconclusive. Here, we conducted a dose–response meta-analysis of prospective cohort studies in order to investigate the correlation between magnesium intake and the risk of cardiovascular disease (CVD), type 2 diabetes […]

Dietary magnesium intake and the risk of cardiovascular disease, type ...



Author: Jae Chung Background: The present study aimed to investigate the mental health status in patients with asthma and assess the effects of asthma on suicidal ideation and attempts using a representative sample from Korea. Methods: Individual-level data were obtained from 228,744 participants (6372 with asthma and 222,372 without asthma) […]

Suicidal ideation and suicide attempts among asthma


Author: Sarah Moore Background: Loss of upper limb function affects up to 85 % of acute stroke patients. Recovery of upper limb function requires regular intensive practise of specific upper limb tasks. To enhance intensity of practice interventions are being developed to encourage patients to undertake self-directed exercise practice. Most interventions […]

Wristband Accelerometers to motiVate arm Exercise after Stroke (WAVES): study ...



Author: Paul Territo Recent advancements in PET instrumentation have made the non-invasive assessment of cardiovascular function in small animals a reality. The majority of small animal PET systems use stationary detector gantries, thus affording high temporal resolution imaging of cardiac function. Systems designed to maximize spatial resolution and detection sensitivity […]

Measurement of cardiovascular function using a novel view-sharing PET reconstruction ...


Author: Carl Hörnsten Background: Few studies have investigated factors associated with depression among elderly people with and without stroke concurrently, using identical settings, procedures and study variables. The aim was to investigate the prevalence of stroke and depression and to compare the factors associated with depression in people with and […]

The prevalence of stroke and depression and factors associated with ...



Author: Xiaohong Xu Platelets are central mediators of thrombosis and hemostasis. At the site of vascular injury, platelet accumulation (i.e. adhesion and aggregation) constitutes the first wave of hemostasis. Blood coagulation, initiated by the coagulation cascades, is the second wave of thrombin generation and enhance phosphatidylserine exposure, can markedly potentiate […]

Platelets and platelet adhesion molecules: novel mechanisms of thrombosis and ...







Author: Carol Cancelliere Background: Work disability is a major personal, financial and public health burden. Predicting future work success is a major focus of research.ObjectivesTo identify common prognostic factors for return-to-work across different health and injury conditions and to describe their association with return-to-work outcomes. Methods: Medline, Embase, PsychINFO, Cinahl, […]

Factors affecting return to work after injury or illness: best ...


Author: Roberta Caorsi The deficiency of Adenosine Deaminase 2 (DADA2) is a new autoinflammatory disease characterised by an early onset vasculopathy with livedoid skin rash associated with systemic manifestations, CNS involvement and mild immunodeficiency.This condition is secondary to autosomal recessive mutations of CECR1 (Cat Eye Syndrome Chromosome Region 1) gene, mapped […]

Monogenic polyarteritis: the lesson of ADA2 deficiency



Author: Litten Bertelsen Background: Cardiovascular magnetic resonance (CMR) is considered the gold standard of cardiac volumetric measurements. Flow in the aortic root is often measured at the sinotubular junction, even though placing the slice just above valve level may be more precise. It is unknown how much flow measurements vary at […]

Flow measurement at the aortic root – impact of location ...


Author: Susanna Calling Background: Living in a socially deprived neighborhood is associated with lifestyle risk factors, e.g., smoking, physical inactivity and unhealthy diet, as well as an increased risk of cardiovascular disease, i.e., coronary heart disease and stroke. The aim was to study whether the odds of cardiovascular disease vary […]

Impact of neighborhood resources on cardiovascular disease: a nationwide six-year ...



Author: Jürgen Rehm Background: Although alcohol consumption has long been considered as a risk factor for chronic disease, the relationship to cardiovascular disease (CVD) is complex and involves at least two dimensions: average volume of alcohol consumption and patterns of drinking. The objective of this contribution was to estimate the […]

Modelling the impact of alcohol consumption on cardiovascular disease mortality ...


Author: Lucie Canel Background: Heatstroke is a life-threatening condition defined by failure of heat load dissipation, resulting in a core temperature higher than 40 °C (104 °F) associated with neurological dysfunction. Topiramate may cause anhidrosis, potentially resulting in heatstroke, as reported especially in children.Case presentationA 57-year-old Caucasian man was admitted […]

Topiramate-induced severe heatstroke in an adult patient: a case report