Chronic Anxiety


Author: Maureen Markle-Reid Background: Depressive symptoms in older home care clients are common but poorly recognized and treated, resulting in adverse health outcomes, premature institutionalization, and costly use of health services. The objectives of this study were to examine the feasibility and acceptability of a new six-month interprofessional (IP) nurse-led […]

An interprofessional nurse-led mental health promotion intervention for older home ...


Author: Joanne Woodford Background: Increased life expectancy has resulted in a greater provision of informal care within the community for patients with chronic physical health conditions. Informal carers are at greater risk of poor mental health, with one in three informal carers of stroke survivors experiencing depression. However, currently no […]

Supported cognitive-behavioural self-help versus treatment-as-usual for depressed informal carers of ...



Author: Nancy A Neilan Background: An altered intestinal mucosal barrier has been demonstrated in subsets of patients with IBS and FAP and may be an additional biological factor contributing to symptom generation in children with FD. The objective of this study was to determine if intestinal permeability is increased in […]

Intestinal permeability in children/adolescents with functional dyspepsia


Author: Mengjun Wu Background: Generic preference-based measures such as the EQ-5D and SF-6D have been criticised for being narrowly focused on a sub-set of dimensions of health. Our study aims to explore whether long-standing health conditions have an incremental impact on subjective well-being alongside the EQ-5D. Methods: Using data from […]

Examining the incremental impact of long-standing health conditions on subjective ...



Author: Bulent Turan Background: Comorbidity of migraine with anxiety and depression may play a role in the link between migraine and obesity. We examined the moderating and mediating roles of ghrelin in the relationship between depression (and anxiety) and body weight in newly diagnosed migraineurs. Methods: Participants were 63 newly […]

The impact of depression and ghrelin on body weight in ...


Author: Maria Isabel Hernandez Background: Prepubertal hypertrichosis is a reportedly benign condition characterized by an excessive growth of vellous hair in non-androgen dependent areas of the body compared to the amount usually present in normal subjects of the same age, race and sex. Although this condition is usually considered idiopathic […]

Hormonal profile and androgen receptor study in prepubertal girls with ...



Author: Ilona Juraskova The article by Korfage and colleagues in this issue of Breast Cancer Research highlights the importance of enabling women to make informed choices about breast cancer chemoprevention. Decision aids have the potential to improve knowledge and decision-making in this context, but they do not guarantee increased uptake […]

Decision aids for breast cancer chemoprevention


Author: Rafat Hussain Background: University students are often perceived to have a privileged position in society and considered immune to ill-health and disability. There is growing evidence that a sizeable proportion experience poor physical health, and that the prevalence of psychological disorders is higher in university students than their community […]

Physical and mental health perspectives of first year undergraduate rural ...



Author: Tanja Jovanovic Several mental illnesses, including anxiety, can manifest during development, with onsets in late childhood. Understanding the neurobiological underpinnings of risk for anxiety is of crucial importance for early prevention and intervention approaches. Translational neuroscience offers tools to investigate such mechanisms in human and animal models. The current […]

Translational neuroscience measures of fear conditioning across development: applications to ...


Author: Yi-Long Yang Background: A lot of empirical studies have been conducted to evaluate the prevalence of depression and anxiety among Chinese adults with cancer. We aimed to conduct a meta-analysis in order to evaluate the prevalence and odds ratios of depression and anxiety in Chinese adults with cancer compared […]

The prevalence of depression and anxiety among Chinese adults with ...



Author: Marie Thi Tran Background: Multiple chemical sensitivity (MCS) is a chronic condition of unknown etiology. MCS is characterized by recurrent nonspecific symptoms from multiple organ systems in response to chemical exposures in concentrations that are normally tolerated by the majority of the population. The symptoms may have severe impact […]

Transcranial pulsed electromagnetic fields for multiple chemical sensitivity: study protocol ...


Author: Julia K Moore Background: To describe the rates, indications, and adverse effects of psychotropic drug prescription in a specialist tertiary hospital child and adolescent eating disorder service. Methods: Retrospective case note study of all active eating disorder patients (N = 115) over the period of treatment from referral to […]

Psychotropic drug prescribing in an Australian specialist child and adolescent ...



Author: Guowei Li Background: The role of vitamin D in management of depression is unclear. Results from observational and emerging randomized controlled trials (RCTs) investigating the efficacy of vitamin D in depression lack consistency – with some suggesting a positive association while others show a negative or inconclusive association. Methods: […]

Efficacy of vitamin D supplementation in depression in adults: a ...


Author: Rhiannon Phillips Background: Self-harm is common in adolescents, but it is often unreported and undetected. Available screening tools typically ask directly about self-harm and suicidal ideation. Although in an ideal world, direct enquiry and open discussion around self-harm would be advocated, non-psychiatric professionals in community settings are often reluctant […]

Could a brief assessment of negative emotions and self-esteem identify ...



Author: Athanasios Tselebis Background: The presence of anxiety and depressive symptoms in COPD patients has been acknowledged for many years. The preponderance of recent studies supports the utility of pulmonary rehabilitation programs to reduce the levels of depression and anxiety in these patients. The aim of this study is to […]

A pulmonary rehabilitation program reduces levels of anxiety and depression ...


Author: Stefan G Hofmann The goal of this review is to examine the clinical studies on d-cycloserine, a partial glutamatergic N-methyl-D-aspartate agonist, as an augmentation strategy for exposure procedures during cognitive behavioral therapy for anxiety disorders. Although cognitive behavioral therapy and anxiolytic medications are more effective than placebo for treating […]

D-Cycloserine as an augmentation strategy for cognitive behavioral therapy of ...



Author: Federica Casini Background: Evidences from literature suggest that Primary Care Physicians’ (PCPs) knowledge and attitude about psychological and pharmacological treatments of anxiety and depressive disorders could influence their clinical practice. The aim of the study is double: 1) to assess PCPs’ opinions about antidepressants (ADs) and psychotherapy for the […]

Primary care Physicians' perspective on the management of anxiety and ...


Author: Sally Adams Background: We have developed a new paradigm that targets the recognition of facial expression of emotions. Here we report the protocol of a randomised controlled trial of the effects of emotion recognition training on mood in a sample of individuals with depressive symptoms over a 6-week follow-up […]

Effects of emotion recognition training on mood among individuals with ...



Author: Zainab B Abdurrahman Background: Insufficient knowledge of food allergy and anaphylaxis has been identified by caregivers as an important barrier to coping, and a potential cause of fear and anxiety, particularly for those with children newly diagnosed with food allergy.The purpose of the study was to better understand the […]

Experiencing a first food allergic reaction: a survey of parent ...


Author: Petr Bob Background: Somatoform dissociation is a specific form of dissociation with somatic manifestations represented in the form of ‘pseudoneurological’ symptoms due to disturbances or alterations of normal integrated functions of consciousness, memory or identity mainly related to trauma and other psychological stressors. With respect to the distinction between […]

'Pseudoneurological' symptoms, dissociation and stress-related psychopathology in healthy young adults



Author: Boris Drozdek Background: Legal status and other resettlement stressors are known to impact mental health of asylum seekers and refugees. However, the ways in which they interact with treatment of posttraumatic stress disorder (PTSD) with these populations is still poorly understood. The aim of this study was to examine […]

Is legal status impacting outcomes of group therapy for posttraumatic ...


Author: Scott J Webster IntroductionDespite the extensive mechanistic and pathological characterization of the APP/PS1 knock-in mouse model of Alzheimer’s disease (AD), very little is known about the AD- relevant behavioral deficits in this model. Characterization of the baseline behavioral performance in a variety of functional tasks and identification of the […]

Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model ...



Author: David Lawrence Background: High rates of smoking and lower rates of smoking cessation are known to be associated with common mental disorders such as anxiety and depression, and with individual and community measures of socioeconomic status. It is not known to what extent mental illness and socioeconomic status might […]

Smoking, mental illness and socioeconomic disadvantage: analysis of the Australian ...


Author: Baltasar Rodero Background: Psychological flexibility has been suggested as a fundamental process in health. The Psychological Inflexibility in Pain Scale (PIPS) is one of the scales employed for assessing psychological inflexibility in pain patients. The aim of this study was to validate the Spanish version of the PIPS and […]

Validation of a Spanish version of the psychological inflexibility in ...