Psychiatric Disorders


Author: Angelo Compare Background: Evidence demonstrates that physical exercise and psychological wellbeing are closely interlinked, particularly in older-aged women. However, research investigating how different forms of exercise influence mental health in older-aged women is underdeveloped. Methods: A randomized controlled trial (N = 300) will assess the relative effectiveness of two […]

PAHA study: Psychological Active and Healthy Aging: psychological wellbeing, proactive ...


Author: Johannes Thome Modern molecular psychiatry benefits immensely from the scientific and technological advances of general neuroscience (including genetics, epigenetics, and proteomics). This "progress" of molecular psychiatry, however, is to a degree "unilateral" and "epiphytic" should the development of the corresponding theoretical frameworks and conceptualization tools that allow contextualization of […]

Decennium of Karl Jaspers's general psychopathology: implications for molecular psychiatry



Author: Ying Liang Background: Urbanization has accelerated in China, and a large amount of arable land has been transformed into urban land. Moreover, the number of landless peasants has continually increased. Peasants lose not only their land, but also a series of rights and interests related with land. The problems […]

Landless female peasants living in urban villages in China have ...


Author: Michelle Collinson Background: Around 150,000 people each year attend hospitals in England due to self-harm, many of them more than once. Over 5,000 people die by suicide each year in the UK, a quarter of them having attended hospital in the previous year because of self-harm. Self-harm is a […]

MIDSHIPS: Multicentre Intervention Designed for Self-Harm using Interpersonal Problem-Solving: protocol ...



Author: Ole Grønli Background: Previous studies have found an association between psychiatric disorders and vitamin D deficiency, but most studies have focused on depression. This study aimed to establish the prevalence of vitamin D deficiency in elderly patients with a wider range of psychiatric diagnoses.MethodThe study included elderly patients (>64 […]

Vitamin D deficiency is common in psychogeriatric patients, independent of ...


Author: Joanne Woodford Background: Increased life expectancy has resulted in a greater provision of informal care within the community for patients with chronic physical health conditions. Informal carers are at greater risk of poor mental health, with one in three informal carers of stroke survivors experiencing depression. However, currently no […]

Supported cognitive-behavioural self-help versus treatment-as-usual for depressed informal carers of ...



Author: Kerry NL Avery Background: The diagnosis of prostate cancer (PC) can provide a trigger for dietary change, and there is evidence that healthier diets may improve quality of life and clinical outcomes. However, men’s views about dietary change in PC survivorship are largely unknown. This multi-centre qualitative interview study […]

The importance of dietary change for men diagnosed with and ...


Author: Julian G Simmons Background: Puberty is a critical developmental phase in physical, reproductive and socio-emotional maturation that is associated with the period of peak onset for psychopathology. Puberty also drives significant changes in brain development and function. Research to date has focused on gonadarche, driven by the hypothalamic-pituitary-gonadal axis, […]

Study protocol: imaging brain development in the childhood to adolescence ...



Author: Matthew Hyett Background: Cognitive disturbances in depression are pernicious and so contribute strongly to the burden of the disorder. Cognitive function has been traditionally studied by challenging subjects with modality-specific psychometric tasks and analysing performance using standard analysis of variance. Whilst informative, such an approach may miss deeper perceptual […]

Bias and discriminability during emotional signal detection in melancholic depression


Author: Julie A Wright Background: Reliable, valid and theoretically consistent measures that assess a parent’s self-efficacy for helping a child with obesity prevention behaviors are lacking.Objectives: To develop measures of parental self-efficacy for four behaviors: 1) helping their child get at least 60 minutes of moderate intensity physical activity every […]

Assessing parental self-efficacy for obesity prevention related behaviors



Author: Monalisa Cesarino Gomes Background: Dental caries, traumatic dental injury (TDI) and malocclusion are common oral health conditions among preschool children and can have both physical and psychosocial consequences. Thus, it is important to measure the impact these on the oral health-related quality of life (OHRQoL) of children. The aim […]

Impact of oral health conditions on the quality of life ...


Author: Leona Hakkaart-van Roijen Background: There is an 80% prevalence of two or more psychiatric symptoms in psychogeriatric patients. Multiple psychiatric symptoms (MPS) have many negative effects on quality of life of the patient as well as on caregiver burden and competence. Irrespective of the effectiveness of an intervention programme, […]

Economic evaluation alongside a single RCT of an integrative psychotherapeutic ...



Author: Laura N Gitlin Background: Behavioral symptoms accompanying dementia are associated with increased health care costs, reduced quality of life and daily functioning, heightened family caregiver burden, and nursing home placement. Standard care typically involves pharmacologic agents, but these are, at best, modestly effective, carry serious risks, including mortality, and […]

A non-pharmacologic approach to address challenging behaviors of veterans with ...


Author: Gerwyn Morris Background: ‘Encephalomyelitis disseminata’ (multiple sclerosis) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are both classified as diseases of the central nervous system by the World Health Organization. This review aims to compare the phenomenological and neuroimmune characteristics of MS with those of ME/CFS.DiscussionThere are remarkable phenomenological and neuroimmune […]

Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable ...



Author: Annina Ropponen Background: Occupations and psychosocial working conditions have rarely been investigated as predictors of disability pension in population-based samples. This study investigated how occupational group and psychosocial working conditions are associated with future disability pension due to musculoskeletal diagnoses, accounting for familial factors in the associations. Methods: A […]

Register-based data of psychosocial working conditions and occupational groups as ...


Author: Rafat Hussain Background: University students are often perceived to have a privileged position in society and considered immune to ill-health and disability. There is growing evidence that a sizeable proportion experience poor physical health, and that the prevalence of psychological disorders is higher in university students than their community […]

Physical and mental health perspectives of first year undergraduate rural ...



Author: Lotta Nybergh Background: Few population-based studies assessing IPV among randomly selected women and men have been conducted in Sweden. Hence, the aim of the current study was to explore self-reported exposure, associated factors, social and behavioral consequences of and reasons given for using psychological, physical and sexual intimate partner […]

Self-reported exposure to intimate partner violence among women and men ...


Author: Michael Berk Background: We now know that depression is associated with a chronic, low-grade inflammatory response and activation of cell-mediated immunity, as well as activation of the compensatory anti-inflammatory reflex system. It is similarly accompanied by increased oxidative and nitrosative stress (O&NS), which contribute to neuroprogression in the disorder. […]

So depression is an inflammatory disease, but where does the ...



Author: Charles B Nemeroff The recent release of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) by the American Psychiatric Association has led to much debate. For this forum article, we asked BMC Medicine Editorial Board members who are experts in the field of psychiatry […]

DSM-5: a collection of psychiatrist views on the changes, controversies, ...


Author: David Kupfer In this podcast we talk to Prof David Kupfer about the challenges, controversies and future directions of DSM-5 by considering other research frameworks and classification systems of disease, and how this revised psychiatric diagnostic manual will impact global mental health classification and the field of medicine.The podcast […]

The DSM-5 – an interview with David Kupfer



Author: Falko F Sniehotta Background: Physical activity (PA) in older adults is influenced by a range of environmental, demographic, health-related, social, and psychological variables. Social cognitive psychological models assume that all influences on behaviour operate indirectly through the models constructs, i.e., via intention and self-efficacy. We evaluated direct, indirect, and […]

Psychological theory in an interdisciplinary context: psychological, demographic, health-related, social, ...


Author: Jonas Tesarz Background: Non-specific chronic back pain (CBP) is often accompanied by psychological trauma, but treatment for this associated condition is often insufficient.Nevertheless, despite the common co-occurrence of pain and psychological trauma, a specific trauma-focused approach for treating CBP has been neglected to date. Accordingly, eye movement desensitization and […]

Effects of eye movement desensitization and reprocessing (EMDR) on non-specific ...



Author: Gabriel R Cojocaru Ageing is associated with changes in the function of various organ systems. Changes in the cardiovascular system affect both directly and indirectly the function in a variety of organs, including the brain, with consequent neurological (motor and sensory performance) and cognitive impairments, as well as leading […]

Post-stroke depression and the aging brain


Author: Bachok Norsa¿adah Background: Epilepsy, a chronic disorder of brain characterised by a predisposition to generate epileptic seizures, has an effect on the psychosocial well-being of sufferers. Measuring the quality of life (QOL) of people with epilepsy (PWE) is increasingly recognized as an important component of clinical management. QOL measures […]

The quality of life of people with epilepsy at a ...