Ulcers


Author: Nikolai V Kuznetsov Background: Glucocorticoids (GCS) remain one of the mainstay treatments in the management of ulcerative colitis (UC) but up to a third of patients will ultimately fail to respond and progress to a more severe and difficult to manage disease state. Previous clinical studies suggest that the […]

Biomarkers can predict potential clinical responders to DIMS0150 a toll-like ...


Author: Mohammed Al-Jaghbeer Background: The hemoglobin threshold for transfusion of red blood cells in patients with acute gastrointestinal (GI) bleeding is controversial. We compared the efficacy and safety of a restrictive transfusion strategy with those of a liberal transfusion strategy. Methods: Objective: The objective was to prove that the restrictive […]

Blood transfusion for upper gastrointestinal bleeding: is less more again?



Author: Qiang Li Background: Pressure ulcer (PU) is common in immobile elderly patients, and there are some research works to investigate a preventive and curative method, but not to find sufficient effectiveness. The aim of this study is to clarify the clinical effectiveness on wound healing in patients with PU […]

Hydrogen water intake via tube-feeding for patients with pressure ulcer ...


Author: Jian-Hui Xie Background: A traditional Chinese Medicine (TCM) formula, HZJW, has been applied in clinics in China for gastrointestinal disorders. However, the therapeutic mechanism underlying its efficacy and safety remained to be defined. The present investigation was undertaken to evaluate the formula HZJW for its gastroprotective potential, possible effect […]

Gastroprotective and anti-Helicobacter pylori potential of herbal formula HZJW: safety ...



Author: Masaki Ujihara Background: Ulcerative colitis (UC) often occurs in women of childbearing age. Compared to Western countries, however, few studies have investigated the impact of UC on the progress of pregnancy in Asian populations. Methods: We retrospectively examined 91 pregnancies in 64 patients with UC experienced at our hospital […]

Importance of appropriate pharmaceutical management in pregnant women with ulcerative ...


Author: Jayakanthan Kabeerdoss Background: Alterations in the fecal bacterial flora occur in inflammatory bowel disease (IBD). We examined the abundance and diversity of Clostridium leptum group, an important group of carbohydrate-fermenting bacteria, in the feces of patients with IBD and compared them with healthy controls. Methods: Seventeen healthy controls (HC), […]

Clostridium leptum group bacteria abundance and diversity in the fecal ...



Author: Hui-qing Lv Background: Our study aims to determine whether response surface methodology can optimize the extraction of dietary fiber from Maixiansan. Methods: A Box–Behnken design was employed to optimize the extraction parameters, including alpha-amylase concentration (X1: 0.3 — 0.5%), enzymolysis time (X2: 30 — 60 min) and NaOH content […]

Optimization of technology for dietary fiber extraction from Maixiansan by ...




Author: Stephanie Venn-Watson Herpesviruses have been recognized in marine mammals, but their clinical relevance is not always easy to assess. A novel otarine herpesvirus-3 (OtHV3) was detected in a geriatric California sea lion (Zalophus californianus), and using a newly developed quantitative PCR assay paired with histology, OtHV3 was associated with […]

Clinical relevance of novel Otarine herpesvirus-3 in California sea lions ...


Author: Caroline Biver-Dalle Background: Since the introduction of sentinel lymph node biopsy (SLNB), its use as a standard of care for patients with clinically node-negative cutaneous melanoma remains controversial. We wished to evaluate our experience of SLNB for melanoma. Methods: A single center observational cohort of 203 melanoma patients with […]

Sentinel lymph node biopsy in melanoma: Our 8-year clinical experience ...